Bernard Jégou, a senior author on the study at the French National Institute of Health and Medical Research, said that he believes that there is no problem in people taking ibuprofen to alleviate pain in the short term but he warns against taking the drug for months on end if it was not absolutely necessary.
While reducing pain signals in the brain, ibuprofen also lowers the male sex hormone testosterone. In the men receiving ibuprofen, levels of luteinizing hormone were up, and the ratio of testosterone to luteinizing hormone dropped.
The team of investigators from Denmark, France and China found that within two week these men had an elevated risk of compensated hypogonadism, "a condition prevalent among elderly men and associated with reproductive and physical disorders", researchers note. While the testosterone levels in the men taking ibuprofen had not changed, researchers found their pituitary glands were boosting testosterone production anyway, inducing the compensated hypogonadism. "Based on these data, I personally would be very reluctant to take ibuprofen for longer than the 10 days normally indicated on the packet".
The study suggests that taking ibuprofen in doses common among athletes can lead to a hormonal condition linked to male infertility. In the group, the men who took 600 mg of Ibuprofen (the equivalent of three tablets) twice a day developed a condition called compensated hypogonadism.
It is known to increase the risk of heart attacks and stroke if taken regularly in high doses for a long time.
The drugs are considered "anti-androgenic", which means they lower the amount of hormones present in males.
When struggling to get pregnant, couples will immediately try to find the source of the issue, but a small new study has revealed that ibuprofen could be a potential sperm killer, and it's something all trying couples should read.
A popular pain medication often popped by men who suffer minors aches and pains related to sports may be linked to infertility, according to a new study.
The study also investigated several other hormones produced by the testes that were found to be reduced by ibuprofen.
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